Cancer surveillance and distress among adult pathogenic TP53 germline variant carriers in Germany: A multicenter feasibility and acceptance survey.

doi:10.1002/cncr.33004

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

Cancer surveillance and distress among adult pathogenic TP53 germline variant carriers in Germany: A multicenter feasibility and acceptance survey.

Cancer - 1 Sept 2020

Rippinger Nathalie, Fischer Christine, Haun Markus W, Rhiem Kerstin, Grill Sabine, Kiechle Marion, Cremer Friedrich W, Kast Karin, Nguyen Huu P, Ditsch Nina, Kratz Christian P, Vogel Julia, Speiser Dorothee, Hettmer Simone, Glimm Hanno, Fröhling Stefan, Jäger Dirk, Seitz Stephan, Hahne Andrea, Maatouk Imad, Sutter Christian, Schmutzler Rita K, Dikow Nicola, Schott Sarah

Abstract excerpt

BACKGROUND: Li-Fraumeni syndrome (LFS) is a high-risk cancer predisposition syndrome caused by pathogenic germline variants of TP53. Cancer surveillance has noted a significant survival advantage in individuals with LFS; however, little is known about the feasibility, acceptance, and psychosocial effects of such a program. METHODS: Pathogenic TP53 germline variant carriers completed a 7-part questionnaire...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Genetic Testing

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Germ-Line Mutation

Share to Germany

Share to Heterozygote

Share to Li-Fraumeni Syndrome

Share to Neoplasms

Share to Tumor Suppressor Protein p53

Share to Young Adult

Source

Open in PubMed

Identifiers

PMID: 32557628
DOI: 10.1002/cncr.33004

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Cancer surveillance and distress among adult pathogenic TP53 germline variant carriers in Germany: A multicenter feasibility and acceptance survey.PMID 32557628Read ↗

Genetic Testing in Li-Fraumeni Syndrome: Uptake and Psychosocial ConsequencesSemantic proximity Read ↗

Psychological functioning in persons considering genetic counseling and testing for Li–Fraumeni syndromeSemantic proximity Read ↗

Health Behavior and Cancer Prevention among Adults with Li-Fraumeni Syndrome and Relatives in Germany-A Cohort Description.Semantic proximity Read ↗

Psychosocial interventions and needs among individuals and families with Li-Fraumeni syndrome: A scoping review.Semantic proximity Read ↗

Health professionals' practice for young people with, or at risk of, Li-Fraumeni syndrome: An Australasian survey.Semantic proximity Read ↗

Uptake of Risk-Reducing Measures, Cascade Testing, and Related Challenges Among Carriers of Breast Cancer-Associated Germline Pathogenic Variants in Mexico.Semantic proximity Read ↗

The psychosocial effects of the Li-Fraumeni Education and Early Detection (LEAD) program on individuals with Li-Fraumeni syndrome.Semantic proximity Read ↗

Obstacles in genetic testing for germline BRCA1/2 pathogenic mutations in patients with primary breast and ovarian cancer in Switzerland.Semantic proximity Read ↗

Families' and health care professionals' attitudes towards Li-Fraumeni syndrome testing in children: A systematic review.Semantic proximity Read ↗

The Experiences and Needs of Individuals with a Variant of Uncertain Significance on Genetic Tests for Hereditary Cancer Syndromes:A Grounded Theory Study.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.