Article

New models to study plasma cells in mouse based on the restriction of IgJ expression to antibody secreting cells

2020-08-14

Abstract excerpt

<h4>ABSTRACT</h4> Plasma cells (PC) represent the last stage of B cell development and are mainly characterized by their capacity of secreting large quantities of antibodies. They can be implicated in a broad-spectrum of neoplastic disorders, including Multiple Myeloma, Waldenstrom macroglobulinemia or Monoclonal Gammopathy of Clinical Significance, all characterized by the abnormal proliferation of a PC clone. U...

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Literature Corpus work: 7ad7fea6-fddd-58a7-b9fb-3316b8696be4
DOI: 10.1101/2020.08.13.249441

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