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Promoter ChIP-chip analysis in mouse testis reveals Y chromosome occupancy by HSF2

6 Aug 2008

Abstract excerpt

The mammalian Y chromosome is essential for spermatogenesis, which is characterized by sperm cell differentiation and chromatin condensation for acquisition of correct shape of the sperm. Deletions of the male-specific region of the mouse Y chromosome long arm (MSYq), harboring multiple copies of a few genes, lead to sperm head defects and impaired fertility. Using chromatin immunoprecipitation on promoter...

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Share to Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
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PMID: 18682557
DOI: 10.1073/pnas.0800620105

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