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Characterization of HSFY, a novel AZFb gene on the Y chromosome with a possible role in human spermatogenesis

16 Feb 2004

Abstract excerpt

HSFY (heat shock transcription factor, Y chromosome) has been mapped in the AZFb region of the Y chromosome, whose deletion results in severe male infertility. HSFY belongs to the heat shock factor family that has been shown to be implicated in spermatogenesis both in animals and humans. We report the characterization of the genomic structure, the number of copies on the Y chromosome and the expression of the...

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PMID: 14985478
DOI: 10.1093/molehr/gah036

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