Article
Pathway-based evaluation of 380 candidate genes and lung cancer susceptibility suggests the importance of the cell cycle pathway.
Carcinogenesis - 1 Oct 2008
Hosgood H Dean, Menashe Idan, Shen Min, Yeager Meredith, Yuenger Jeff, Rajaraman Preetha, He Xingzhou, Chatterjee Nilanjan, Caporaso Neil E, Zhu Yong, Chanock Stephen J, Zheng Tongzhang, Lan Qing
Abstract excerpt
Common genetic variation may play an important role in altering lung cancer risk. We conducted a pathway-based candidate gene evaluation to identify genetic variations that may be associated with lung cancer in a population-based case-control study in Xuan Wei, China (122 cases and 111 controls). A total of 1260 single-nucleotide polymorphisms (SNPs) in 380 candidate genes for lung cancer were successfully...
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