Article
A two-stage random forest-based pathway analysis method.
PloS one - 1 Jan 2012
Chung Ren-Hua, Chen Ying-Erh
Abstract excerpt
Pathway analysis provides a powerful approach for identifying the joint effect of genes grouped into biologically-based pathways on disease. Pathway analysis is also an attractive approach for a secondary analysis of genome-wide association study (GWAS) data that may still yield new results from these valuable datasets. Most of the current pathway analysis methods focused on testing the cumulative main effects of...
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