Article
Potentially functional variants of Wnt signaling pathway genes predict risk of primary lung cancer in Chinese Han population.
Scientific reports - 31 Jul 2026
Chen Xiaohui, Xu Qiuping, Huang Linlin, Hong Wencong, Xu Tingshan, Yu Liying, Zeng Yiming, He Fei, Xu Yuan
Abstract excerpt
Wnt signaling is a highly conserved pathway that regulates cell proliferation, differentiation, apoptosis and stem cell self-renewal, which has implications for embryonic development and tumorigenesis. We investigated the potential role of candidate single nucleotide polymorphisms (SNPs) of Wnt signaling pathway genes with computational evidence of regulatory potential on lung cancer in Chinese Han patients. The...
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