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Polymorphisms of COX/PEG2 pathway-related genes are associated with the risk of lung cancer: A case-control study in China.

International immunopharmacology - 1 Jul 2022

Liang Xiaohua, Wang Jian, Liu Yongshi, Wei Lin, Tian Feng, Sun Jianyong, Han Guoliang, Wang Yan, Ding Chao, Guo Zhaolei

Abstract excerpt

BACKGROUND: The COX/PGE2 pathway is widely involved in the development of tumors and the regulation of tumor immune cells such as T cells, NK cells and DCs. However, little information is available on the single nucleotide polymorphisms (SNPs) of COX/PGE2 pathway-related genes in patients with lung cancer. METHODS: Seven SNPs of the PTGS2, PTGER2 and PTGIS genes were genotyped in a case-control cohort including...

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PMID: 35430434
DOI: 10.1016/j.intimp.2022.108763

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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