Article
Pathway-based analysis using genome-wide association data from a Korean non-small cell lung cancer study.
PloS one - 1 Jan 2013
Lee Donghoon, Lee Geon Kook, Yoon Kyong-Ah, Lee Jin Soo
Abstract excerpt
Pathway-based analysis, used in conjunction with genome-wide association study (GWAS) techniques, is a powerful tool to detect subtle but systematic patterns in genome that can help elucidate complex diseases, like cancers. Here, we stepped back from genetic polymorphisms at a single locus and examined how multiple association signals can be orchestrated to find pathways related to lung cancer susceptibility. We...
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