Article
Comparison of pathway analysis approaches using lung cancer GWAS data sets.
PloS one - 1 Jan 2012
Fehringer Gordon, Liu Geoffrey, Briollais Laurent, Brennan Paul, Amos Christopher I, Spitz Margaret R, Bickeböller Heike, Wichmann H Erich, Risch Angela, Hung Rayjean J
Abstract excerpt
Pathway analysis has been proposed as a complement to single SNP analyses in GWAS. This study compared pathway analysis methods using two lung cancer GWAS data sets based on four studies: one a combined data set from Central Europe and Toronto (CETO); the other a combined data set from Germany and MD Anderson (GRMD). We searched the literature for pathway analysis methods that were widely used, representative of...
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