Article
Single-step real-time PCR to quantify hepatitis B virus and distinguish genotype D from non-D genotypes.
Journal of viral hepatitis - 1 Apr 2011
Amini-Bavil-Olyaee S, Pourkarim M R, Schaefer S, Mahboudi F, Van Ranst M, Adeli A, Trautwein C, Tacke F
Abstract excerpt
Hepatitis B virus (HBV) viral load and its genotype play important roles in clinical outcome, management of disease and response to antiviral therapy. In many parts of the world such as Europe or the Middle East, distinguishing HBV genotype D from non-D is most relevant for treatment decisions, because genotype D-infected patients respond poorly to interferon-based therapeutic regimens. Here, we developed an...
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