Article
YMDD mutations and genotypes of hepatitis B virus in northern China.
Japanese journal of infectious diseases - 1 Feb 2006
Li Di, Gu Hong-Xi, Zhang Shu-Yun, Zhong Zhao-Hua, Zhuang Min, Hattori Toshio
Abstract excerpt
The objective of this research was to determine the relationship between YMDD mutations and the genotypes of hepatitis B virus (HBV) during lamivudine treatment. HBV genotypes were determined by nested PCR with 6 pairs of HBV genotype-specific primers (A to F) in serum specimens from 142 hepatitis B patients receiving lamivudine antiviral therapy. YMDD mutations were detected by fluorescent hybridization bioprobe...
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