Article
Association of APOE epsilon4 allele with survival in amyotrophic lateral sclerosis.
Journal of the neurological sciences - 15 Sept 2001
Drory V E, Birnbaum M, Korczyn A D, Chapman J
Abstract excerpt
APOE epsilon4 allele is associated with poorer outcome in degenerative neurological diseases. Its role in amyotrophic lateral sclerosis (ALS) is still unclear. The aim of the present study was to further analyze the association of APOE epsilon4 allele with progression and survival of ALS. One hundred consecutive ALS patients (53 males) and 133 controls were genotyped for the APOE epsilon4 allele. The association...
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