Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

p120 and Kaiso RegulateHelicobacter pylori-induced Expression of Matrix Metalloproteinase-7

24 Jul 2008

Abstract excerpt

Helicobacter pylori is the strongest known risk factor for gastric adenocarcinoma, yet only a fraction of infected persons develop cancer. One H. pylori constituent that augments disease risk is the cytotoxin-associated gene (cag) pathogenicity island, which encodes a secretion system that translocates bacterial effector molecules into host cells. Matrix metalloproteinase (MMP)-7, a member of a family of enzymes...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer-related gene regulation
Share to Galectins and Cancer Biology
Share to Helicobacter pylori-related gastroenterology studies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 18653469
DOI: 10.1091/mbc.e08-03-0283

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

p120 and Kaiso RegulateHelicobacter pylori-induced Expression of Matrix Metalloproteinase-7PMID 18653469Read ↗

Helicobacter pylori stimulates gastric epithelial cell MMP-1 secretion via CagA-dependent and -independent ERK activation.Semantic proximity Read ↗

Proteolytic Landscapes in Gastric Pathology and CancerogenesisSemantic proximity Read ↗

CagA Associates with c‐Met, E‐Cadherin, and p120‐Catenin in a Multiproteic Complex That SuppressesHelicobacter pylori–Induced Cell‐Invasive PhenotypeSemantic proximity Read ↗

Helicobacter pylori Encoding the Pathogenicity Island Activates Matrix Metalloproteinase 1 in Gastric Epithelial Cells via JNK and ERKSemantic proximity Read ↗

IV.Helicobacter pyloristrain-specific activation of signal transduction cascades related to gastric inflammationSemantic proximity Read ↗

CagA mediates epigenetic regulation to attenuate let-7 expression in Helicobacter pylori -related carcinogenesisSemantic proximity Read ↗

Cag pathogenicity island-specific responses of gastric epithelial cells to Helicobacter pylori infection.Semantic proximity Read ↗

Polymorphisms of matrix metalloproteinase-7 and chymase are associated with susceptibility to and progression of gastric cancer in Japan.Semantic proximity Read ↗

Transforming growth factor-B1 and matrix metalloproteinase-7 promoter variants induce risk for Helicobacter pylori-associated gastric precancerous lesions.Semantic proximity Read ↗

Functional antagonism between <i>Helicobacter pylori</i> CagA and vacuolating toxin VacA in control of the NFAT signaling pathway in gastric epithelial cellsSemantic proximity Read ↗

Activation of IL-8 gene expression by Helicobacter pylori is regulated by transcription factor nuclear factor-kappa B in gastric epithelial cells.Semantic proximity Read ↗

NF-κB activation and potentiation of proinflammatory responses by the <i>Helicobacter pylori</i> CagA proteinSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.