Article
Helicobacter pylori Encoding the Pathogenicity Island Activates Matrix Metalloproteinase 1 in Gastric Epithelial Cells via JNK and ERK
2 Dec 2005
Abstract excerpt
Helicobacter pylori colonizes the human gastric epithelium and induces an inflammatory response that is a trigger for gastric carcinogenesis. Matrix metalloproteinases (MMPs) have recently been shown to be up-regulated in gastric epithelial cells infected with H. pylori and might contribute to the pathogenesis of peptic ulcer. The aim of this study was to extend the knowledge about the effect of H. pylori...
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