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Proteolytic Landscapes in Gastric Pathology and Cancerogenesis

22 Feb 2022

Abstract excerpt

Gastric cancer is a leading cause of cancer-related death, and a large proportion of cases are inseparably linked to infections with the bacterial pathogen and type I carcinogen Helicobacter pylori. The development of gastric cancer follows a cascade of transformative tissue events in an inflammatory environment. Proteases of host origin as well as H. pylori-derived proteases contribute to disease progression at...

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PMID: 35269560
DOI: 10.3390/ijms23052419

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