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Article

Association of MDR1, CYP3A418B, and CYP3A53 polymorphisms with cyclosporine pharmacokinetics in Chinese renal transplant recipients.

European journal of clinical pharmacology - 1 Nov 2008

Qiu Xiao-Yan, Jiao Zheng, Zhang Ming, Zhong Long-Jin, Liang Hui-Qi, Ma Chun-Lai, Zhang Liang, Zhong Ming-Kang

Abstract excerpt

OBJECTIVE: The objective of this study was to retrospectively evaluate the effects of MDR1, CYP3A4*18B, and CYP3A5*3 genetic polymorphisms on cyclosporine A (CsA) pharmacokinetics in Chinese renal transplant patients during the first month after transplantation. METHODS: A total of 103 renal transplant recipients receiving CsA were genotyped for MDR1 (C1236T, G2677T/A, and C3435T), CYP3A4*18B, and CYP3A5*3. The...

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Identifiers

PMID: 18636247
DOI: 10.1007/s00228-008-0520-8

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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