Article
Association of CYP3A polymorphisms with the pharmacokinetics of cyclosporine A in early post-renal transplant recipients in China.
Acta pharmacologica Sinica - 1 Dec 2012
Meng Xiang-guang, Guo Cheng-xian, Feng Guo-qing, Zhao Ying-chun, Zhou Bo-Ting, Han Jian-le, Chen Xin, Shi Yong, Shi Hong-yao, Yin Ji-ye, Peng Xiang-dong, Pei Qi, Zhang Wei, Wang Guo, He Meng, Liu Min, Yang Jing-ke, Zhou Hong-hao
Abstract excerpt
AIM: To evaluate retrospectively the association of cytochrome P450 3A (CYP3A) and ATP-binding cassette sub-family B member 1 (ABCB1) gene polymorphisms with the pharmacokinetics of cyclosporine A (CsA) in Chinese renal transplant patients. METHODS: One hundred and twenty-six renal transplant patients were recruited. Blood samples were collected, and corresponding clinical indices were recorded on the seventh day...
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