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Article

Population pharmacokinetic study of cyclosporine in Chinese renal transplant recipients.

European journal of clinical pharmacology - 1 Jun 2011

Chen Bing, Zhang WeiXia, Gu ZhiDong, Li Juan, Zhang YuXin, Cai WeiMin

Abstract excerpt

PURPOSE: To establish the population pharmacokinetic (PPK) model of cyclosporine (CsA) in Chinese renal transplant recipients and evaluate the influence of various indexes including CYP3A5 and MDR1 genetic polymorphism on pharmacokinetic parameters. METHODS: Trough (C(0)) and peak (C(2)) CsA concentration were monitored conventionally after renal transplantation. C(0) and C(2) were collected for 5 months in 146...

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Source

Identifiers

PMID: 21161198
DOI: 10.1007/s00228-010-0959-2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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