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Article

Associations of ABCB1, NFKB1, CYP3A, and NR1I2 polymorphisms with cyclosporine trough concentrations in Chinese renal transplant recipients.

Acta pharmacologica Sinica - 1 Apr 2013

Zhang Yu, Li Jia-li, Fu Qian, Wang Xue-ding, Liu Long-shan, Wang Chang-xi, Xie Wen, Chen Zhuo-jia, Shu Wen-ying, Huang Min

Abstract excerpt

AIM: Cyclosporine requires close therapeutic drug monitoring because of its narrow therapeutic index and marked inter-individual pharmacokinetic variation. In this study, we investigated the associations of CYP3A4, CYP3A5, ABCB1, NFKB1, and NR1I2 polymorphisms with cyclosporine concentrations in Chinese renal transplant recipients in the early period after renal transplantation. METHODS: A total of 101 renal...

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Share to ATP Binding Cassette Transporter, Subfamily B
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 23503472
DOI: 10.1038/aps.2012.200
PMCID: PMC4002791

Genes

ABCB1
NFKB1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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