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Article

Influence of ABCB1, CYP3A418B and CYP3A53 polymorphisms on cyclosporine A pharmacokinetics in bone marrow transplant recipients.

Pharmacological reports : PR - 1 Jan 2011

Qiu Feng, He Xiao-Jing, Sun Ya-Xin, Li-Ling Jesse, Zhao Li-Mei

Abstract excerpt

The aim of this study was to retrospectively evaluate the effect of polymorphisms in the CYP3A4, CYP3A5 and ABCB1 genes on the dose-adjusted concentration and dose requirement of cyclosporine A(CsA) in Chinese recipients during the early period after bone marrow or hematopoietic stem cell transplantation. Ninety-one bone marrow transplant recipients were genotyped by the polymerase chain reaction-restriction...

Read the complete abstract on PubMed

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Share to ATP Binding Cassette Transporter, Subfamily B
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Bone Marrow Transplantation

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Source

Identifiers

PMID: 21857093
DOI: 10.1016/s1734-1140(11)70594-1

Genes

ABCB1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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