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Article

Neither replication nor simulation supports a role for the axon guidance pathway in the genetics of Parkinson's disease.

PloS one - 16 Jul 2008

Li Yonghong, Rowland Charles, Xiromerisiou Georgia, Lagier Robert J, Schrodi Steven J, Dradiotis Efthimios, Ross David, Bui Nam, Catanese Joseph, Aggelakis Konstantinos, Grupe Andrew, Hadjigeorgiou Georgios

Abstract excerpt

Susceptibility to sporadic Parkinson's disease (PD) is thought to be influenced by both genetic and environmental factors and their interaction with each other. Statistical models including multiple variants in axon guidance pathway genes have recently been purported to be capable of predicting PD risk, survival free of the disease and age at disease onset; however the specific models have not undergone...

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Identifiers

PMID: 18628988
DOI: 10.1371/journal.pone.0002707
PMCID: PMC2442653

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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