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Article

Genetic risk and age in Parkinson's disease: Continuum not stratum.

Movement disorders : official journal of the Movement Disorder Society - 1 May 2015

Nalls Mike A, Escott-Price Valentina, Williams Nigel M, Lubbe Steven, Keller Margaux F, Morris Huw R, Singleton Andrew B

Abstract excerpt

BACKGROUND: Recent genomewide association study meta-analyses have identified 28 loci associated with risk of Parkinson's disease (PD). We sought to investigate whether these genetic risk factors are associated with PD age at onset. METHODS: Genetic risk scores from these loci were calculated for 6,249 cases. Linear regression tested associations between cumulative genetic risk and PD age at onset. RESULTS:...

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Identifiers

PMID: 25778492
DOI: 10.1002/mds.26192
PMCID: PMC5217457

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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