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Article

Genome-wide linkage screen in familial Parkinson disease identifies loci on chromosomes 3 and 18.

American journal of human genetics - 1 Apr 2009

Gao Xiaoyi, Martin Eden R, Liu Yutao, Mayhew Gregory, Vance Jeffery M, Scott William K

Abstract excerpt

Parkinson disease (PD) is a complex, multifactorial neurodegenerative disease with substantial evidence for genetic risk factors. We conducted a genome-wide linkage screen of 5824 single-nucleotide polymorphisms in 278 families of European, non-Hispanic descent to localize regions that harbor susceptibility loci for PD. By using parametric and nonparametric linkage analyses and allowing for genetic heterogeneity...

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Identifiers

PMID: 19327735
DOI: 10.1016/j.ajhg.2009.03.005
PMCID: PMC2667976

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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