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Article

A genomic pathway approach to a complex disease: axon guidance and Parkinson disease.

PLoS genetics - 1 Jun 2007

Lesnick Timothy G, Papapetropoulos Spiridon, Mash Deborah C, Ffrench-Mullen Jarlath, Shehadeh Lina, de Andrade Mariza, Henley John R, Rocca Walter A, Ahlskog J Eric, Maraganore Demetrius M

Abstract excerpt

While major inroads have been made in identifying the genetic causes of rare Mendelian disorders, little progress has been made in the discovery of common gene variations that predispose to complex diseases. The single gene variants that have been shown to associate reproducibly with complex dise...

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Identifiers

PMID: 17571925
DOI: 10.1371/journal.pgen.0030098
PMCID: PMC1904362

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17571925-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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