Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Analysis of mutations in DNA isolated from plasma and stool of colorectal cancer patients.

Gastroenterology - 1 Aug 2008

Diehl Frank, Schmidt Kerstin, Durkee Kristine H, Moore Kent J, Goodman Steve N, Shuber Anthony P, Kinzler Kenneth W, Vogelstein Bert

Abstract excerpt

BACKGROUND & AIMS: Somatic mutations provide uniquely specific markers for the early detection of neoplasia that can be detected in DNA purified from plasma or stool of patients with colorectal cancer. The primary purpose of the present investigation was to determine the parameters that were critical for detecting mutations using a quantitative assay. A secondary purpose was to compare the results of plasma and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Colorectal Neoplasms
Share to DNA, Neoplasm

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Flow Cytometry

Share to Gene Expression Regulation, Neoplastic

Share to Magnetics

Share to Predictive Value of Tests

Share to Reproducibility of Results

Source

Open in PubMed Open full text

Identifiers

PMID: 18602395
DOI: 10.1053/j.gastro.2008.05.039
PMCID: PMC2820386

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Analysis of mutations in DNA isolated from plasma and stool of colorectal cancer patients.PMID 18602395Read ↗

Clinical relevance of alterations in quantity and quality of plasma DNA in colorectal cancer patients: based on the mutation spectra detected in primary tumors.Semantic proximity Read ↗

Detection and quantification of mutations in the plasma of patients with colorectal tumors.Semantic proximity Read ↗

Combined DNA Analysis from Stool and Blood Samples Improves Tumor Tracking and Assessment of Clonal Heterogeneity in Localized Rectal Cancer Patients.Semantic proximity Read ↗

Detection of mutations associated with colorectal cancer in DNA from whole-gut lavage fluid.Semantic proximity Read ↗

Detection of mutant K-ras DNA in plasma or serum of patients with colorectal cancer.Semantic proximity Read ↗

High-resolution melting assay (HRMA) is a simple and sensitive stool-based DNA Test for the detection of mutations in colorectal neoplasms.Semantic proximity Read ↗

Detection of the mutated K-Ras biomarker in colorectal carcinoma.Semantic proximity Read ↗

Gene mutations in advanced colonic polyps: potential marker selection for stool-based mutated human DNA assays for colon cancer screening.Semantic proximity Read ↗

Detection of Epigenetic Changes in Fecal DNA as a Molecular Screening Test for Colorectal Cancer: A Feasibility StudySemantic proximity Read ↗

Detection of stool DNA mutations before and after treatment of colorectal neoplasia.Semantic proximity Read ↗

A blood-based DNA test for colorectal cancer screening.Semantic proximity Read ↗

Analysis of KRAS mutations in circulating tumor DNA and colorectal cancer tissue.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.