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Combined DNA Analysis from Stool and Blood Samples Improves Tumor Tracking and Assessment of Clonal Heterogeneity in Localized Rectal Cancer Patients.

Technology in cancer research & treatment - 1 Jan 2024

Parigger Thomas, Gassner Franz Josef, Drothler Stephan, Scherhäufl Christian, Hödlmoser Alexandra, Schultheis Lena, Bakar Aryunni Abu, Huemer Florian, Greil Richard, Geisberger Roland, Weiss Lukas, Zaborsky Nadja

Abstract excerpt

Objectives: In this study, stool samples were evaluated for tumor mutation analysis via a targeted next generation sequencing (NGS) approach in a small patient cohort suffering from localized rectal cancer. Introduction: Colorectal cancer (CRC) causes the second highest cancer-related death rate worldwide. Thus, improvements in disease assessment and monitoring that may facilitate treatment allocation and allow...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 38766867
DOI: 10.1177/15330338241252706
PMCID: PMC11104029

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