Article
Detection of stool DNA mutations before and after treatment of colorectal neoplasia.
Cancer - 15 Jan 2006
Syngal Sapna, Stoffel Elena, Chung Daniel, Willett Christopher, Schoetz David, Schroy Paul, Jagadeesh Deepa, Morel Kathleen, Ross Michael
Abstract excerpt
BACKGROUND: Whether stool DNA abnormalities arise solely from colorectal neoplastic lesions or are due to more pervasive field effects is not known. In the current study, the authors conducted a prospective multicenter study to evaluate the performance of stool-based DNA testing in a large cohort and to examine whether the findings before treatment persist after surgical resection and/or adjuvant therapy....
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