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Gene mutations in advanced colonic polyps: potential marker selection for stool-based mutated human DNA assays for colon cancer screening.

Clinical colorectal cancer - 1 Nov 2003

Berger Barry M, Vucson Beverly M, Ditelberg Jeremy S

Abstract excerpt

The detection and removal of advanced colonic polyps (ACPs) can help prevent the development of colorectal cancer. A set of DNA mutations known to be associated with colorectal carcinoma was tested against resected ACPs to determine the set s potential utility as a marker panel for ACPs. A sensitive mutation marker panel could be used by stool-based assays that look for mutated human DNA to detect the presence of...

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PMID: 14706178
DOI: 10.3816/CCC.2003.n.024

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