Article
A blood-based DNA test for colorectal cancer screening.
Discovery medicine - 1 Feb 2007
Schmidt Kerstin, Diehl Frank
Abstract excerpt
Early detection of colorectal tumors through the identification of mutant DNA in serum or plasma could have a substantial impact on morbidity and mortality. Somatic mutations are specific biomarkers for neoplastic cells, but their detection requires sensitive assays, as the number of circulating mutant molecules is small compared to the number of normal DNA molecules. A newly developed method can provide this...
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