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Article

Antibiotic resistance--what's dosing got to do with it?

Critical care medicine - 1 Aug 2008

Roberts Jason A, Kruger Peter, Paterson David L, Lipman Jeffrey

Abstract excerpt

OBJECTIVE: This review seeks to identify original research articles that link antibiotic dosing and the development of antibiotic resistance for different antibiotic classes. Using this data, we seek to apply pharmacodynamic principles to assist clinical practice for suppressing the emergence of resistance. Concepts such as mutant selection window and mutant prevention concentration will be discussed. DATA...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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PMID: 18596628
DOI: 10.1097/CCM.0b013e318180fe62

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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