Article
New concepts in antimicrobial susceptibility testing: the mutant prevention concentration and mutant selection window approach.
Veterinary dermatology - 1 Oct 2009
Blondeau Joseph M
Abstract excerpt
Current measurements of antimicrobial susceptibility or resistance utilize a standardized bacterial inoculum (10(5) cfu/mL) exposed to varying drug concentrations in a test tube. Following incubation under ideal conditions, the lowest drug concentration inhibiting growth is the minimum inhibitory concentration (MIC). When the MIC exceeds the amount of drug that can be safely achieved in the body, we call these...
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