Article
Therapeutic options in an era of decreasing antimicrobial susceptibility.
Journal of chemotherapy (Florence, Italy) - 1 Feb 2002
Drlica K, Schmitz F J
Abstract excerpt
Antimicrobial resistance among human pathogens has evolved to the multidrug-resistant phase. Consequently, preserving antimicrobial efficacy is now an important clinical consideration when selecting an agent for therapy. A new, in vitro measure of potency called the mutant prevention concentration (MPC) allows clinicians to select antibacterials on the basis of an agent's ability to restrict the selection of...
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