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Article

Optimizing dosage to prevent emergence of resistance - lessons from in vitro models.

Current opinion in pharmacology - 1 Oct 2011

Singh Renu, Tam Vincent H

Abstract excerpt

The widespread emergence of resistance to antimicrobial agents has taken mammoth dimension and warrants immediate steps to minimize it. Pharmacokinetics/pharmacodynamics of antimicrobial agents, differences among bacterial species, and time-dependent changes in the bacterial population are important factors involved in the development of drug resistance. The key to minimizing resistance lies in understanding how...

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PMID: 21868287
DOI: 10.1016/j.coph.2011.07.009

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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