Article
Predicting and preventing antimicrobial resistance utilizing pharmacodynamics: Part I gram positive bacteria.
Expert opinion on drug metabolism & toxicology - 1 Jan 2016
Linder Kristin E, Nicolau David P, Nailor Michael D
Abstract excerpt
INTRODUCTION: Antimicrobial resistance is a potentially inevitable consequence of widespread use of antibiotics in the healthcare system. An enhanced understanding of pharmacodynamic (PD) targets that prevent antimicrobial resistance development will improve currently availably therapies and help to guide future drug development strategies. Current in vitro methods to predict bacterial resistance to...
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