Article
Antibiotic exposure as a risk factor for emergence of resistance: the influence of concentration.
Symposium series (Society for Applied Microbiology) - 1 Jan 2002
Gould I M, MacKenzie F M
Abstract excerpt
Evolution of antibiotic resistance (AR) is increasingly perceived as a major clinical problem. The use of bactericidal antibiotics may protect against this, to some extent, by eradication of the pathogen, but the borders between cidal and inhibitory activity in the patient are often blurred. In addition, there are clinical reasons why eradication of the pathogen may not always be desirable. Antibiotic dosing...
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