Article
Characterization of the humoral immune response to islet antigen 2 in children with newly diagnosed type 1 diabetes.
European journal of endocrinology - 1 Jul 2008
Mäkinen Anna, Härkönen Taina, Ilonen Jorma, Knip Mikael
Abstract excerpt
OBJECTIVE: To characterize the humoral immune response to islet antigen 2 (IA-2) in patients with newly diagnosed type 1 diabetes (T1D), we compared the profile of epitope- and isotype-specific IA-2 antibodies (IA-2A) between children with a humoral immune response restricted to IA-2 and children with a broad response including insulin autoantibodies (IAA) and antibodies to glutamic acid decarboxylase (GADA) in...
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