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Article

Combined positivity for HLA DQ2/DQ8 and IA-2 antibodies defines population at high risk of developing type 1 diabetes.

Diabetologia - 1 Apr 2005

Decochez K, Truyen I, van der Auwera B, Weets I, Vandemeulebroucke E, de Leeuw I H, Keymeulen B, Mathieu C, Rottiers R, Pipeleers D G, Gorus F K

Abstract excerpt

AIMS/HYPOTHESIS: Prevention trials in first-degree relatives of type 1 diabetic patients are hampered by large interindividual differences in progression rate to diabetes. We investigated whether specific combinations of immune and genetic markers can identify subgroups with more homogeneous progression to clinical onset. METHODS: Antibodies against islet cell cytoplasm (ICA), insulin (IAA), glutamate...

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PMID: 15756536
DOI: 10.1007/s00125-005-1702-x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Combined positivity for HLA DQ2/DQ8 and IA-2 antibodies defines population at high risk of developing type 1 diabetes.PMID 15756536Read ↗

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