Article
Primary islet autoantibody at initial seroconversion and autoantibodies at diagnosis of type 1 diabetes as markers of disease heterogeneity.
Pediatric diabetes - 1 Mar 2018
Ilonen Jorma, Lempainen Johanna, Hammais Anna, Laine Antti-Pekka, Härkönen Taina, Toppari Jorma, Veijola Riitta, Knip Mikael
Abstract excerpt
OBJECTIVE: The relationship between patterns of islet autoantibodies at diagnosis and specificity of the first islet autoantibody at the initiation of autoimmunity was analyzed with the aim of identifying patterns informative of the primary autoantibodies. METHODS: Information about a single first autoantibody at seroconversion and autoantibody data at diagnosis were available for 128 children participating in...
Topics
- Autoantibodies
- Autoimmunity
- Biomarkers
- Cohort Studies
- Diabetes Mellitus, Type 1
- Family Health
- Female
- Finland
- Follow-Up Studies
- Genetic Predisposition to Disease
- Glutamate Decarboxylase
- Humans
- Ikaros Transcription Factor