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Article

IA-2 antibody isotypes and epitope specificity during the prediabetic process in children with HLA-conferred susceptibility to type I diabetes.

Clinical and experimental immunology - 1 Apr 2006

Hoppu S, Härkönen T, Ronkainen M S, Simell S, Hekkala A, Toivonen A, Ilonen J, Simell O, Knip M

Abstract excerpt

The natural history of preclinical diabetes is partly characterized, but there is still limited information on the dynamics of the immune response to beta-cell autoantigens during the course of preclinical disease. The aim of this work was to assess the maturation of the humoral immune response to the protein tyrosine phosphatase(PTP)-related proteins (IA-2 and IA-2beta) in preclinical type I diabetes (TID)....

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Identifiers

PMID: 16542366
DOI: 10.1111/j.1365-2249.2006.03033.x
PMCID: PMC1809627

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Source receipt: pubmed, retrieved 7 Sept 2026.

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IA-2 antibody isotypes and epitope specificity during the prediabetic process in children with HLA-conferred susceptibility to type I diabetes.PMID 16542366Read ↗

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