Article
HLA-DR-DQ haplotypes and specificity of the initial autoantibody in islet specific autoimmunity.
Pediatric diabetes - 1 Nov 2020
Mikk Mari-Liis, Pfeiffer Sophie, Kiviniemi Minna, Laine Antti-Pekka, Lempainen Johanna, Härkönen Taina, Toppari Jorma, Veijola Riitta, Knip Mikael, Ilonen Jorma
Abstract excerpt
OBJECTIVE: We aimed to clarify the association of various HLA risk alleles with different types of autoantibodies initiating islet specific autoimmunity. METHODS: Follow-up cohorts from the Finnish Type 1 Diabetes Prediction and Prevention (DIPP) study and children diagnosed with type 1 diabetes (T1D) from the Finnish Pediatric Diabetes Register (FPDR) were analyzed for the presence of autoantibodies to insulin...
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