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Article

Humoral beta-cell autoimmunity in relation to HLA-defined disease susceptibility in preclinical and clinical type 1 diabetes.

American journal of medical genetics - 30 May 2002

Knip Mikael, Kukko Marika, Kulmala Petri, Veijola Riitta, Simell Olli, Akerblom Hans K, Ilonen Jorma

Abstract excerpt

We have studied the relationship between diabetes-associated autoantibodies and various HLA genotypes and alleles in patients with newly diagnosed type 1 diabetes, in non-diabetic siblings and in children representing the general population to test the hypothesis that specific HLA genes regulate the humoral immune response to various autoantigens. Among the newly diagnosed patients we observed that those carrying...

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Source

Identifiers

PMID: 12116176
DOI: 10.1002/ajmg.10343

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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