Article
Can mitochondrial DNA mutations in circulating white blood cells and serum be used to detect breast cancer?
Breast (Edinburgh, Scotland) - 1 Oct 2008
Losanoff Julian E, Zhu Weizhu, Qin Wenyi, Mannello Ferdinando, Sauter Edward R
Abstract excerpt
Circulating mitochondrial DNA (mtDNA) affected by mutations have been detected in melanoma, prostate cancer, and digestive neoplasms involving the pancreas, liver, and the colon. We sought to detect such mutations in women with breast cancer to assess if the method could be used to aid in the diagnosis of breast cancer. Blood was collected and mtDNA extracted; 27 samples included 14 patients who had breast cancer...
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