Article
Mitochondrial DNA mutations in Malaysian female breast cancer patients.
PloS one - 1 Jan 2020
Omasanggar Raevathi, Yu Choo Yee, Ang Geik Yong, Emran Nor Aina, Kitan Normayah, Baghawi Anita, Falparado Ahmad Atiki, Abdullah Maizaton Atmadini, Teh Lay Kek, Maniam Sandra
Abstract excerpt
Cancer development has been ascribed with diverse genetic variations which are identified in both mitochondrial and nuclear genomes. Mitochondrial DNA (mtDNA) alterations have been detected in several tumours which include lung, colorectal, renal, pancreatic and breast cancer. Several studies have explored the breast tumour-specific mtDNA alteration mainly in Western population. This study aims to identify mtDNA...
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