Article
An A10398G mitochondrial DNA alteration is related to increased risk of breast cancer, and associates with Her2 positive receptor.
Mitochondrial DNA. Part A, DNA mapping, sequencing, and analysis - 1 Jan 2020
Jahani Mohammad Mehdi, Azimi Meibody Azita, Karimi Talie, Banoei Mohammad Mehdi, Houshmand Massoud
Abstract excerpt
Breast cancer is the most common malignancy and the second leading cause of cancer deaths among women worldwide after lung cancer. Mitochondria play a central role in the regulation of cellular function, metabolism, and cell death in cancer cells. We aim to examine the mitochondrial polymorphisms of complex I in association with breast cancer in an Iranian cohort.This experimental study includes 53 patients with...
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