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Article

Detection of mitochondrial DNA mutations by high-throughput sequencing in the blood of breast cancer patients.

International journal of molecular medicine - 1 Jan 2014

Li Lin Hai, Kang Tao, Chen Lidan, Zhang Weiyun, Liao Yang, Chen Jianyun, Shi Yuling

Abstract excerpt

Mitochondrial DNA mutations have been identified in serveral types of cancer. In breast cancer, germline and somatic mitochondrial DNA (mtDNA) mutations have been identified. A number of mtDNA mutations in breast cancer have been identified in protein-coding regions (in protein-coding genes, such as ND2, COX3, ND4, ND5 and CytB). Mutations in these structure proteins cause impaired electron transport function and...

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Identifiers

PMID: 24253185
DOI: 10.3892/ijmm.2013.1559

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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