Article
Breast cancer as a mitochondrial disorder (Review).
Oncology reports - 1 Apr 2009
Plak Katarzyna, Czarnecka Anna M, Krawczyk Tomasz, Golik Pawel, Bartnik Ewa
Abstract excerpt
Mitochondria have been implicated in cell transformation since Otto Warburg considered 'respiration damage' to be a pivotal feature of cancer cells. Numerous somatic mitochondrial DNA (mtDNA) mutations have been found in various types of neoplasms, including breast cancer. Establishing the mtDNA mutation pattern in breast cancer cells may enhance the specificity of cancer diagnostics, detection and prediction of...
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