Article
Correlational study on mitochondrial DNA mutations as potential risk factors in breast cancer.
Oncotarget - 24 May 2016
Li Linhai, Chen Lidan, Li Jun, Zhang Weiyun, Liao Yang, Chen Jianyun, Sun Zhaohui
Abstract excerpt
The presented study performed an mtDNA genome-wide association analysis to screen the peripheral blood of breast cancer patients for high-risk germline mutations. Unlike previous studies, which have used breast tissue in analyzing somatic mutations, we looked for germline mutations in our study, since they are better predictors of breast cancer in high-risk groups, facilitate early, non-invasive diagnoses of...
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