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Article

Mannose-binding lectin deficiency is associated with early onset of polyarticular juvenile rheumatoid arthritis: a cohort study.

Arthritis research & therapy - 1 Jan 2008

Dolman Koert M, Brouwer Nannette, Frakking Florine N J, Flatø Berit, Tak Paul P, Kuijpers Taco W, Førre Oystein, Smerdel-Ramoya Anna

Abstract excerpt

BACKGROUND: Mannose-binding lectin (MBL) is an innate immune protein. The aim of our study was to determine whether genetically determined MBL deficiency is associated with susceptibility to juvenile rheumatoid arthritis (JRA) and whether MBL2 genotypes are associated with JRA severity. METHODS: In a retrospective cohort study of 218 patients with polyarthritis (n = 67) and oligoarthritis (n = 151), clinical and...

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Source

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Identifiers

PMID: 18334024
DOI: 10.1186/ar2386
PMCID: PMC2453777

Genes

MBL2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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