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Article

Behavioral abnormalities and dopamine reductions in sdy mutant mice with a deletion in Dtnbp1, a susceptibility gene for schizophrenia.

Biochemical and biophysical research communications - 22 Aug 2008

Hattori Satoko, Murotani Tomotaka, Matsuzaki Shinsuke, Ishizuka Tomoko, Kumamoto Natsuko, Takeda Masatoshi, Tohyama Masaya, Yamatodani Atsushi, Kunugi Hiroshi, Hashimoto Ryota

Abstract excerpt

Genetic susceptibility plays an important role in the pathogenesis of schizophrenia. Genetic evidence for an association between the dysbindin-1 gene (DTNBP1: dystrobrevin binding protein 1) and schizophrenia has been repeatedly reported in various populations worldwide. Thus, we performed behavioral analyses on homozygous sandy (sdy) mice, which lack dysbindin-1 owing to a deletion in the Dtnbp1 gene. Our...

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Source

Identifiers

PMID: 18555792
DOI: 10.1016/j.bbrc.2008.06.016

Genes

DTNBP1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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